Respen-A™ is currently only available as a compounded prescription medication from the following pharmacies:

Pure Compounding Pharmacy
603 East Diehl Rd, #131
Naperville, IL 60563

Hopewell Pharmacy
1 West Broad Street
Hopewell, NJ 08525

Wellness Pharmacy
3401 Independence Drive, Ste 231
Birmingham, AL 35209
Toll Free 1-800-227-2627




How to Apply the Respen-A™ Disc

If your shipment includes a container of calcium/magnesium skin cream, stir it every day prior to dosing to keep it from clumping. IF your skin cream becomes too thick, add Distilled Water, a few drops at a time, till the cream is smooth. The consistency should be such that you can rub it onto/into the skin for two minutes, without it becoming tacky or dry, but not runny enough to where it drips off your arm.

  • IF you are applying the cream to your child, WEAR NITRILE/RUBBER GLOVES so your child receives full benefit of calcium!
  • Do not apply cream to irritated, broken, or cracked skin.
  • Do not get cream on clothing.
  • Store at room temperature. DO NOT FREEZE!
  • Note: If the calcium/magnesium skin cream is exposed to freezing temperatures, the cream will become grainy in texture due to the calcium solidifying. If this happens, add distilled water a few drops at a time, and stir until the skin cream becomes creamy again (about the consistency of a facial skin cream). The grains of calcium will dissolve completely within a few days when the skin cream is stored at room temperature.

    If your child experiences skin irritation or stinging where the calcium skin cream is applied, apply hydrocortisone cream or Aloe Vera gel to the skin first, let dry, then apply the calcium/magnesium skin cream.

    Note: The Respen-A™ 1.0 Disc can lower your intracellular calcium level, so it is very important that you take the recommended amount of calcium and magnesium every day! Symptoms of low calcium include irritability, muscle and joint stiffness and aching, numbness and tingling in the hands, feet, around the mouth, and face. You may need to supplement with magnesium oxide (preferred though other forms are o.k.) if you experience constipation- increase till stools are normal.

    STEP ONE: Apply calcium/magnesium skin cream
    Apply 1 teaspoon (5 ml) of the calcium/magnesium skin cream to your skin every morning, such as your forearms, BEFORE applying the Respen-A™ Disc. Gently rub the calcium/magnesium cream into your skin for a full 2 minutes to ensure adequate absorption, and till it is clear, then rinse the area thoroughly with warm water while rubbing all residue off, and towel dry. The white color in the cream is the calcium- when clear, this indicates that it has been completely absorbed. To avoid over saturation of the skin, which would limit the amount of calcium absorbed, it is recommended to use two application sites, e.g.; both arms. Most parents report that waiting 45 minutes following calcium cream before applying the Respen-A™ Disc delivers better results.

    Fructooligosaccharides (FOS) may be a beneficial supplement to be considered with the Respen-A™ Disc as it is a prebiotic that will assist in calcium and mineral absorption, as well as protect the cells from too much calcium influx that can cause inflammation. FOS has also been shown to decrease cholesterol levels due to its ability to protect the cells from destruction from calcium influx. To achieve these benefits from FOS, it is important that 2,000 mg be taken all at once with breakfast. FOS is available as a tablet, or powder that dissolves easily in water, and has a slightly sweet taste.

    SUPPLEMENTS: From our observation and experience, the diet should not be supplemented with EFA’s, whether in oil form or supplement form, as these are polyunsaturated to super-unsaturated fats that can potentially decrease the effectiveness of the Respen-A™ Disc. It is important to get some Omega-3 unsaturated fat in the diet, and this can be accomplished by eating some fish each week. It is also important to avoid Vitamin D in excess of 400 iu’s a day, L-Glutamine, GABA, Curcumin or Turmeric, Papain, Licorice Root (Anise) often in digestive enzyme supplements, Quercetin, L-Carnitine, L-Carnosine, Tyrosine, Rhodiola, Harmine, Cat’s Claw, Lemon Balm, Kalonji, Milk Thistle, Ashwagandha, Goldenseal, and antioxidants such as alpha lipoic acid (ALA is already really high in these kids!) as these, too, will decrease the effectiveness of the Respen-A™ Disc. Anything high in polyphenols, such as Cistus Tea and olive oils high in polyphenols, will lower the MAO-A*, thus negating the Respen-A™. We have found that those taking no supplements, other than the calcium/magnesium skin cream, the FOS if needed, and inositol or 5-HTP if on a gluten restricted diet or not eating meat respectively, see the best improvements.

    *link to known plants that inhibit MAO-A:

    The FAQ list on the www.respen-a website is far more extensive...for the best success, please review the answers to key questions!

    NOTE: please discuss with your physician before making changes to your supplement program.

    STEP TWO: Apply Respen-A™ Disc
    Make sure the skin is clean and dry. The disc may be applied anywhere on the torso of the body (abdomen, side, hip, back, chest) that is easily accessible and not subject to too much skin stretching or rubbing of clothing. In the case of sensitivity issues, parents have reported that the back, between the shoulder blades, is an adequate spot as the child has a hard time reaching the disc to remove it. In most cases, this sensitivity resolves within 3 days, and the disc can then be transferred to an area that is better for absorption and less likely to become loose due to movement of the body or exterior clothing. A great spot is on the side of the hip, where it can be protected underneath the underwear. This also allows for better absorption because there is fat over the hip bone.

      1) Inspect the skin for any open areas or sores. Do not apply the disc to any areas that have a sore, crack in the skin, or are open.
      2) Open the ZipSeal foil pouch, containing the Respen-A™ Discs, at the tear notch, and remove the sheet of discs. Remove 1 disc. Reseal the remaining sheet of discs in the foil pouch using the ZipSeal closure. DO NOT LEAVE THE SHEET OF DISCS EXPOSED TO AIR AS THIS WILL BEGIN TO MAKE THE FREQUENCY LESS VIABLE.
      3) Apply the disc to the center of a strip of the adhesive tape that has been provided with the Respen-A™, and attach to clean, dry skin, making sure that it is completely sealed down. The adhesive tape is waterproof, so the disc can be worn when showering, bathing or swimming. It is also occlusive, which keeps air out, thus maintaining viability.
      4) Apply 1 disc daily, in the morning, and wear it until bedtime when it will be removed. The disc should be worn for at least 12 hours as there is no carry over, and you'll want to see benefits when you are interacting with your child. The following morning, apply a new disc, rotating application sites so as to not apply a disc in the exact same site on the skin within a 48-hour time interval.
      5) Repeat steps 1 through 4 daily.

    NOTE: It is o.k. to touch the Respen-A™ Disc and move the sides away from the edges of the tape to ensure more adhesive area for a proper seal.

    ADHESIVE INFORMATION: The tape that comes with the disc is occlusive (keeps all air out) and waterproof- both of which are necessary to keep the disc viable. One of the ingredients in the Respen-A™ Disc that keeps it stable is glycerin. Glycerin absorbs water- moisture is in air, and the glycerin attracts moisture. The water clumps together, and this clumping will muffle the frequency of the Respen-A™ Disc, which means you won't get a clear effect. Therefore, DO NOT use any other tape to seal the disc to the skin!

    STORAGE: The Respen-A™ Discs are to be stored at room temperature in the foil ZipSeal package. IF your zipper on the ZipSeal package fails, simply fold the top over a couple of times and use a bag clip on one corner. DO NOT TRANSFER DISCS TO ANY OTHER TYPE OF STORAGE PACKAGE AS THE ZIPSEAL PACKAGE IS OCCLUSIVE, WHICH MEANS IT KEEPS AIR AND LIGHT OUT. The Respen-A™ will lose its viability the longer it is exposed to air.

    If you misplace your tape, this is the information for reordering online (available on Amazon):

    3M BLENDERM 1" x 5 Yd Clear Surgical Plastic / Tape 1525-1 LF Waterproof Hypoallergenic

    Product Description on Amazon: 3M Blenderm Surgical Tape is a latex free, hypoallergenic, occlusive transparent tape designed to provide a barrier from external fluids and contamination. This tape is ideal for protecting wounds and for specialist applications.

    If you are looking for more information on the Respen-A™ Disc, please continue browsing this website.

    We also have a blog that discusses many topics, not only regarding Respen-A™, but other Autism treatments and how they interact with the Respen-A™ Disc:

    If you have any troubleshooting questions about Respen-A™, or any testimonials you would like to share regarding your results of using the Respen-A™ Disc, please call us at 425-870-9366, or message us on the Respen-A™ Facebook page, link shown below. We would love to speak with you!